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Antibodies
Antibodies
Anti-LDL Receptor antibody [EP1553Y]
Anti-LDL Receptor antibody [EP1553Y] from Abcam
(1)
Write a review
Citations:
(120)
Supplier Page
Supplier Page from
Abcam for
Anti-LDL Receptor antibody [EP1553Y]
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-LDL Receptor antibody [EP1553Y]
Company
Abcam
Price
Supplier Page
View Supplier Product Page
Catalog Number
ab52818
Antibody Type
Primary
Clone
EP1553Y
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Quantity
10 UL, 40 UL, 100 UL
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Gene Name
LDLR
Reactivity
Human, Mouse
Target
LDL Receptor
Conjugate/Tag
Unconjugated
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (120)
(21)
Blocking cholesterol efflux mechanism is a potential target for antilymphoma therapy
Cancer science
June 1, 2022
Yano H, Fujiwara Y, Horlad H, Pan C, Kai K, Niino D, Ohsawa K, Higashi M, Nosaka K, Okuno Y,
et al
.
Cell Signaling Technology
),
anti‐SR‐BI
(
NB400‐104
;
Novus Biologicals
), anti‐
ABCA1
(
NB400‐105
;
Novus Biologicals
), anti‐LDLR (
ab52818
;
Abcam
), anti‐phospho‐IRE1 (
ab48187
; Abcam), and anti‐β‐actin (
sc‐47778
;
Santa Cruz Biotechnology
).
(22)
The Metabolic Efficacy of a Cannabidiolic Acid (CBDA) Derivative in Treating Diet- and Genetic-Induced Obesity
International Journal of Molecular Sciences
May 17, 2022
Elad Ben-Cnaan, Anna Permyakova, Shahar Azar, Shira Hirsch, Saja Baraghithy, Liad Hinden, Joseph Tam
binding. Blots were incubated overnight with primary antibodies against LDL receptor (LDLR) (
1:1000
; Cat#
ab52818
,
Abcam
, Cambridge, UK), proprotein convertase subtilisin/kexin type-9 (PCSK9)(
human
) (
1:1000
; Cat#
ab181142
,
(23)
MicroRNA-20a-5p Downregulation by Atorvastatin: A Potential Mechanism Involved in Lipid-Lowering Therapy
International Journal of Molecular Sciences
April 30, 2022
Kathleen Saavedra, Karla Leal, Nicolás Saavedra, Yalena Prado, Isis Paez, Carmen G. Ubilla, Gabriel Rojas, Luis A. Salazar
PVDF
membranes
(Bio-Rad, Hercules, CA, USA). Primary antibodies
anti-LDL receptor
[EP1553Y] (
1:1000
,
ab52818
,
Abcam
, Cambridge, UK) and anti-beta actin [AC-15] (HRP) (
1:20
.000,
ab49900
,
Abcam
, Cambridge, UK) were
(24)
Di’ao Xinxuekang Capsule Improves the Anti-Atherosclerotic Effect of Atorvastatin by Downregulating the SREBP2/PCSK9 Signalling Pathway
Frontiers in Pharmacology
April 28, 2022
Jiyi Liang, Wei Li, Honglin Liu, Xiaofen Li, Chuqiao Yuan, Wenjun Zou, Liping Qu
were bought from Foregene Biotechnology Co., Ltd. (Chengdu, China).
Anti-LDL Receptor
antibody (Cat#:
ab52818
) and anti-
PCSK9
antibody (Cat#:
ab185194
) were purchased from
Abcam
(Cambridgeshire, United Kingdom).
(25)
Identification and New Indication of Melanin-Concentrating Hormone Receptor 1 (MCHR1) Antagonist Derived from Machine Learning and Transcriptome-Based Drug Repositioning Approaches
International Journal of Molecular Sciences
March 30, 2022
Gyutae Lim, Ka Young You, Jeong Hyun Lee, Moon Kook Jeon, Byung Ho Lee, Jae Yong Ryu, Kwang-Seok Oh
Nonspecific binding was blocked with 5% milk and incubated with
1:1000
primary antibody (LDLR Rabbit-mAb, #
ab52818
,
Abcam
) overnight at 4 °C. The secondary antibodies (horseradish peroxidase [HRP]-conjugated mouse anti-rabbit
(26)
LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis
Clinical and translational medicine
January 1, 2022
Shi X, Chen Y, Liu Q, Mei X, Liu J, Tang Y, Luo R, Sun D, Ma Y, Wu W,
et al
.
analysis.
Immunofluorescence
. The lung specimens were fixed in 4% paraformaldehyde and stained with anti‐
LDLR
(
1:2000
,
ab52818
,
Abcam
), anti‐Collagen I (
1:200
,
72026
,
CST
) and/or anti‐SP‐C (
Human
:
1:500
,
ab40879
,
Mouse
:
1:2000
,
(27)
Low Density Lipoprotein Receptor (LDLR) and 3-Hydroxy-3-Methylglutaryl Coenzyme a Reductase (HMGCR) Expression are Associated with Platinum-Resistance and Prognosis in Ovarian Carcinoma Patients
Cancer Management and Research
December 6, 2021
Xueyao Huang, Xuan Wei, Sijing Qiao, Xue Zhang, Rui Li, Shunxue Hu, Hongluan Mao, Peishu Liu
stained using a monoclonal anti-LDLR (diluted
1:500
in phosphate buffer saline (PBS)) produced in rabbit (
ab52818
,
Abcam
, Cambridge, UK) and monoclonal anti-
HMGCR
(diluted
1:50
in PBS) produced in
mouse
(
ab242315
,
(28)
Intratumour heterogeneity in microRNAs expression regulates glioblastoma metabolism
Scientific Reports
December 1, 2021
Huda Alfardus et al.
was blocked by 5% semi-skimmed milk for 1 h at room temperature with monoclonal antibodies for CPT2 (
ab52818
;
Abcam
) at
1:1000
dilution or
GAPDH
(
ab8245
;
Abcam
) at
1:1000
dilution. This was followed by
incubation
(29)
CircMTO1 inhibits ox-LDL-stimulated vascular smooth muscle cell proliferation and migration via regulating the miR-182-5p/RASA1 axis
Molecular Medicine
December 1, 2021
Ningning Ji, Yu Wang, Xinyan Gong, Shimao Ni, Hui Zhang
antibodies against RASA1 (
1:500
;
Abcam
,
ab40677
), a-SMA (
1:500
;
Abcam
,
ab5694
), LDL-receptor (
1:1000
;
Abcam
,
ab52818
), caspase 3 (
1:1000
; Abcam, ab32315), cyclin D1 (
1:1000
;
Abcam
,
ab16663
) and GAPDH (
1:1000
; Sangon,
(30)
LDL mediated delivery of Paclitaxel and MRI imaging probes for personalized medicine applications
Journal of Nanobiotechnology
December 1, 2021
Sahar Rakhshan, Diego Alberti, Rachele Stefania, Valeria Bitonto, Simonetta Geninatti Crich
min); after a further washing with 3 ml of PBS the primary antiLDL receptor monoclonal antibody (
Abcam
ab52818
) was incubated 30 min at 4 °C to cell samples n° 3 (3 µL in 200 μl of 0.1% BSA/PBS). Then 3 ml of PBS
(31)
Generation of a Novel High-Affinity Antibody Binding to PCSK9 Catalytic Domain with Slow Dissociation Rate by CDR-Grafting, Alanine Scanning and Saturated Site-Directed Mutagenesis for Favorably Treating Hypercholesterolemia
Biomedicines
November 27, 2021
Zhengli Bai, Menglong Xu, Ying Mei, Tuo Hu, Panpan Zhang, Manman Chen, Wenxiu Lv, Chenchen Lu, Shuhua Tan
with gDNA Eraser were bought from TaKaRa (Dalian, Liaoning, China). Rabbit anti-LDLR antibody (Cat#
ab52818
) and rabbit anti-PCSK9 antibody (Cat#
ab181142
) were bought from
Abcam
(Cambridge, UK). Glutamine, TMB
(32)
The Effects of Anthocyanin-Rich Bilberry Extract on Transintestinal Cholesterol Excretion
Foods (Basel, Switzerland)
November 18, 2021
Hong J, Kim M, Kim B.
antibody,
Abcam
,
ab30682
Rabbit monoclonal Anti-
HMGCR
antibody,
Abcam
,
ab174830
Rabbit monoclonal
Anti-LDL Receptor
antibody,
Abcam
,
ab52818
Goat
polyclonal Anti-PCSK9 antibody,
Abcam
,
ab28770
Rabbit polyclonal Anti-
ABCG8
antibody,
Abcam
,
ab126493
Monoclonal
(33)
Creation of X-linked Alport syndrome rat model with Col4a5 deficiency
Scientific reports
October 21, 2021
Namba M, Kobayashi T, Kohno M, Koyano T, Hirose T, Fukushima M, Matsuyama M.
(
T9026
), α-SMA (1A4) (
Sigma
, St. Louis, MO); phospho-
Smad3
(
ab52903
), Fibronectin (
ab6328
), LDL receptor (
ab52818
), MMP12 (
ab52897
) (
Abcam
, Cambridge, UK);
Smad3
(#
9523
,
Cell Signaling Technology
, Beverly, MA);
Nephrin
(34)
Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice
Biomolecules
October 6, 2021
Nyandwi JB, Ko YS, Jin H, Yun SP, Park SW, Kim HJ.
Louis, MO, USA). A mouse IL-1β ELISA kit (
ab100704
) and antibodies against ABCA1 (
ab18180
), LDL-R (
ab52818
), and carnitine palmitoyltransferase 1A (CPT1A;
ab53532
) were purchased from
Abcam
(Cambridge, UK).
(35)
Developing a second-generation clinical candidate AAV vector for gene therapy of familial hypercholesterolemia
Molecular Therapy - Methods & Clinical Development
September 10, 2021
Lili Wang, Ilayaraja Muthuramu, Suryanarayan Somanathan, Hong Zhang, Peter Bell, Zhenning He, Hongwei Yu, Yanqing Zhu, Anna P. Tretiakova, James M. Wilson
performed as previously described.25 LDLR and beta-tubulin were detected with rabbit anti-LDLR antibody (
ab52818
;
Abcam
, Cambridge, MA, USA) and rabbit anti-beta-tubulin antibody (
ab6046
;
Abcam
), respectively. Bound
(36)
Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms
Neuron
August 4, 2021
Shi Y, Andhey PS, Ising C, Wang K, Snipes LL, Boyer K, Lawson S, Yamada K, Qin W, Manis M,
et al
.
antibodies: HJ6.8B (for murine apoE, in house), α-tubulin (
Sigma-Aldrich
, Cat#
T5168
),
LDLR
(
Abcam
, Cat#
ab52818
),
Lgmn
(
Santa Cruz
, Cat#
sc-133234
), p4EBP (
Cell signaling
, Cat#
2855
), actin (
Cell signaling
, Cat#
(37)
Transgenic mice for in vivo epigenome editing with CRISPR-based systems
Nature methods
August 1, 2021
Gemberling MP, Siklenka K, Rodriguez E, Tonn-Eisinger KR, Barrera A, Liu F, Kantor A, Li L, Cigliola V, Hazlett MF,
et al
.
1:2000
) at room temp for 2-3 hours, Anti-
Gapdh
(
Cell Signaling
, Cat#
2118L
,
1:5000
), Anti-LDLR (
Abcam
, Cat#
ab52818
,
1:1000
), and anti-Actin (
EMD Millipore
, Cat#
MAB1501
,
1:5000
) overnight at 4°C. After washing, secondary
(38)
Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity
Cells
June 29, 2021
Zapatero-Belinchón FJ, Ötjengerdes R, Sheldon J, Schulte B, Carriquí-Madroñal B, Brogden G, Arroyo-Fernández LM, Vondran FWR, Maasoumy B, von Hahn T,
et al
.
(0.4 µg/mL, rabbit) (
NB400-104
,
Novus Biologicals
, Littleton, USA), α-human LDLr (1.34 µg/mL, rabbit) (
ab52818
,
Abcam
, Cambridge, UK), α-
human
occludin (1.25 µg/mL,
mouse
) (
33–1500
, Invitrogen/Thermo Scientific,
(39)
Rutin and Quercetin Decrease Cholesterol in HepG2 Cells but Not Plasma Cholesterol in Hamsters by Oral Administration
Molecules (Basel, Switzerland)
June 21, 2021
Liang N, Li YM, He Z, Hao W, Zhao Y, Liu J, Zhu H, Kwek E, Ma KY, He WS,
et al
.
Santa Cruz
Biotechonology (Dallas, TX, USA). The antibodies against LXRα (
ab176323
,
1:1000
dilution), LDLR (
ab52818
,
1:500
dilution), and CYP7A1 (
ab65596
,
1:1000
dilution) were purchased from
Abcam
(Cambridge, UK). The
(40)
Fat tissue regulates the pathogenesis and severity of cardiomyopathy in murine chagas disease
PLoS neglected tropical diseases
April 1, 2021
Lizardo K, Ayyappan JP, Oswal N, Weiss LM, Scherer PE, Nagajyothi JF.
Signaling), Low density lipoprotein receptor (LDLR)—specific rabbit monoclonal antibody (
1:1000
dilution,
ab52818
,
Abcam
), Acetyl CoA carboxylase specific rabbit monoclonal antibody (
1:1000
dilution, C83B10, Cell Signaling),
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Reviews
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(1)
8/30/2016
Review of Abcam Anti-LDL Receptor antibody [EP1553Y] (ab52818)
Nneka Mbah
Used this antibody for a western blot to determine LDL Receptor protein levels in U251 glioma cells. Cells were serum starved overnight, incubated with cycloheximide (10ug/ml) to block synthesis of ...
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Anti-LDL Receptor antibody [EP1553Y] from Abcam
Supplier Page
View Supplier Product Page
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